Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28523284 | 0.98 | TDP1 (0.52) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL17710412 | 0.98 | TDP1 (0.52) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL809501 | 0.91 | ALDH1A1 (0.61) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL7937151 | 0.87 | TDP1 (0.59) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10889654 | 0.87 | TDP1 (0.46) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL9572932 | 0.87 | TDP1 (0.46) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL20362192 | 0.87 | KCNH3 (0.54) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10851455 | 0.87 | TDP1 (0.46) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL2937099 | 0.87 | KCNH3 (0.54) | TDP1TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL27484229 | 0.85 | KCNH3 (0.52) | TDP1TSHRALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-111343963-B | Use of physiologically cooling active ingredients and compositions comprising such active ingredients | 巴斯夫欧洲公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023157864-A1 | ORGANIC SEMICONDUCTOR INK, ORGANIC FILM, PHOTOELECTRIC CONVERSION LAYER, METHOD FOR PRODUCING PHOTOELECTRIC CONVERSION LAYER, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | 三菱ケミカル株式会社 | 2023-08-24 | — | — | WO | disclosed |
| WO-2023149473-A1 | MESOIONIC ARYL PYRIDAZINIUM DERIVATIVE OR SALT THEREOF, INSECTICIDE CONTAINING SAME, AND METHOD FOR USING SAME | 日本農薬株式会社 | 2023-08-10 | — | — | WO | disclosed |
| WO-2023112943-A1 | ORGANIC SEMICONDUCTOR INK, PHOTOELECTRIC CONVERSION LAYER, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT | 三菱ケミカル株式会社 | 2023-06-22 | — | — | WO | disclosed |
| CN-112321448-A | Preparation method of amide-containing Mannich type compound | 东华理工大学 | 2021-02-05 | — | — | CN | disclosed |
| US-10696707-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20190135847-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2019-05-09 | — | — | US | disclosed |
| WO-2018103688-A1 | IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3Kdelta INHIBITORS | BEIGENE, LTD. (KY) | 2018-06-14 | — | — | WO | disclosed |
| CN-106749129-A | Pesticidal compound | 先正达参股股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-7780870-B2 | Liquid crystal composition, liquid crystal element, and siloxane polymer | FUJIFILM CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| CN-101548207-A | Optical film and glass | FUJIFILM CORP (JP) | 2009-09-30 | — | — | CN | disclosed |
| US-20090023964-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| US-20080152843-A1 | Liquid Crystal Composition, Liquid Crystal Element, and Siloxane Polymer | FUJIFILM CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1848678-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES | Syngeta Participations AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| US-20070218216-A1 | Light modulating material | FUJIFILM CORPORATION | 2007-09-20 | — | — | US | disclosed |
| WO-2006084663-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006080573-A1 | LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND SILOXANE POLYMER | FUJIFILM CORPORATION (JP) | 2006-08-03 | — | — | WO | disclosed |
| CN-1081676-A | The indoles and the indazole derivatives that are used for the treatment and the prevention of cerebral disorders, their preparation and application | SANKYO CO (JP) | 1994-02-09 | — | — | CN | disclosed |
| US-3968188-A | Process for preparing the pentaerythritol ester of phosphorohalidous acid | MONSANTO COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135847-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | TDP1 4057/4885TSHR 4491/4885ALDH1A1 4446/4885 |
| US-20090023964-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES | HPD, CYP4X1, AZI2 | TDP1 2049/4885TSHR 3047/4885ALDH1A1 123/4885 |
| US-10696707-B2 | Polyene macrolide derivative | ERG28, RPL23, RPL10 | TDP1 4057/4885TSHR 4491/4885ALDH1A1 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.