SCHEMBL5196375

SCHEMBL5196375

CCCCC(Cl)CC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
NPC1 O15118 1/20 0.50
TSHR P16473 1/20 0.50
CES1 P23141 4/20 0.46
CES2 O00748 3/20 0.46
DRD3 P35462 1/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 2/20 0.46
TRPA1 O75762 1/20 0.46
GSK3B P49841 1/20 0.46
HIF1A Q16665 1/20 0.46
L3MBTL1 Q9Y468 5/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5196048 0.95 KMT2A (0.49) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5194063 0.93 CES2 (0.49) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5195867 0.93 CES2 (0.49) KMT2AMEN1NPC1TSHRCES1
SCHEMBL27616858 0.93 CES2 (0.49) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5196176 0.93 CES2 (0.49) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5198198 0.93 CES2 (0.49) KMT2AMEN1NPC1TSHRCES1
Ammonia Solution, Strong SCHEMBL134867 0.92 CES2 (0.47) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5197283 0.91 TSHR (0.52) KMT2AMEN1NPC1TSHRCES1
SCHEMBL5617677 0.85 CYP2C9 (0.48) KMT2AMEN1NPC1GSK3BL3MBTL1
SCHEMBL5195513 0.84 TSHR (0.55) KMT2AMEN1NPC1TSHRCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403260-B1 Optically active epoxy compounds and processes for their production TOSOH CORP (JP) 2007-08-08 EP claimed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US claimed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP claimed
EP-1403260-B1 Optically active epoxy compounds and processes for their production TOSOH CORP (JP) 2007-08-08 EP disclosed
US-7169944-B2 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2007-01-30 US disclosed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063979-A1 Optically active epoxy compounds and processes for their production CYP51A1, CYP11B1, PTGES KMT2A 3888/4885MEN1 2396/4885NPC1 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.