Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5181246 | 0.99 | CETP (0.32) | CETP | |
| Hydrochloric Acid SCHEMBL1901294 | 0.93 | TAS2R14 (0.33) | CETP | |
| Bicarbonate SCHEMBL5214022 | 0.93 | CETP (0.36) | CETP | |
| SCHEMBL4828916 | 0.93 | TAS2R14 (0.33) | CETP | |
| Hydrochloric Acid SCHEMBL1904525 | 0.92 | TAS2R14 (0.32) | CETP | |
| Bicarbonate SCHEMBL5182760 | 0.92 | CETP (0.36) | CETP | |
| SCHEMBL4830749 | 0.91 | TAS2R14 (0.32) | CETP | |
| Hydrochloric Acid SCHEMBL1902431 | 0.87 | CETP (0.34) | CETP | |
| Hydrochloric Acid SCHEMBL1902526 | 0.86 | RXRA (0.31) | CETP | |
| SCHEMBL4831002 | 0.86 | CETP (0.34) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1533292-B1 | DIBENZYLAMINE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2007-02-14 | — | — | EP | claimed |