Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 15/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096995 | 1.00 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5090887 | 0.90 | OPRD1 (0.38) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5094820 | 0.90 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5197378 | 0.86 | OPRM1 (0.42) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5094888 | 0.84 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5095011 | 0.83 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 | |
| SCHEMBL490138 | 0.83 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5094709 | 0.83 | OPRD1 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5090812 | 0.83 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5090930 | 0.82 | OPRD1 (0.48) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836196-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069275-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-29 | — | — | WO | disclosed |