Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.40 |
| ▸ | CA2 | P00918 | 12/20 | 0.40 |
| ▸ | CA9 | Q16790 | 12/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595233 | 0.76 | LIPG (0.40) | CA1CA2CA9ROCK1LPL | |
| SCHEMBL5306031 | 0.75 | PNMT (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2925545 | 0.75 | PNMT (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL959820 | 0.74 | GRIA2 (0.51) | — | |
| SCHEMBL1591339 | 0.74 | GRIA2 (0.51) | — | |
| SCHEMBL11898497 | 0.74 | GRIA2 (0.51) | — | |
| SCHEMBL5272399 | 0.73 | CA1 (0.44) | CA1CA2CA9CA12CA3 | |
| SCHEMBL5272406 | 0.73 | CA1 (0.44) | CA1CA2CA9CA12CA3 | |
| SCHEMBL27857521 | 0.73 | TBXA2R (0.36) | CA1CA2CA9CA12CA7 | |
| SCHEMBL15096664 | 0.72 | LIPG (0.42) | CA1CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786766-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006015829-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |