SCHEMBL5197679

SCHEMBL5197679

Clc1ccc(OCCOC2CCCCO2)cn1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
KDM4C Q9H3R0 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CHRNA3 P32297 6/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CHRNB2 P17787 7/20 0.44
CHRNA4 P43681 7/20 0.44
CHRNB4 P30926 3/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNB1 P11230 1/20 0.42
CHRNB3 Q05901 1/20 0.42
CYP2D6 P10635 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24517557 0.85 KDM4C (0.54) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL17288096 0.84 MEN1 (0.51) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL15732998 0.84 MEN1 (0.51) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL29703952 0.82 KDM4C (0.54) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL17288212 0.82 KDM4C (0.53) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL30225190 0.81 KDM4C (0.49) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL23975779 0.81 KDM4C (0.49) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL30225192 0.81 KDM4C (0.49) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL18106022 0.80 KDM4C (0.44) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL17323672 0.79 KMT2A (0.57) MEN1KMT2AKDM4CNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070275968-A1 Substituted Biphenyl Derivative SANKYO COMPANY, LIMITED (JP) 2007-11-29 US disclosed
EP-1798229-A1 SUBSTITUTED BIPHENYL DERIVATIVE Sankyo Company, Limited (JP) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275968-A1 Substituted Biphenyl Derivative COL2A1, COL1A1, FGFR3 MEN1 3828/4885KMT2A 1587/4885KDM4C 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.