Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121183 | 1.00 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL5197821 | 1.00 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| Hydrochloric Acid SCHEMBL4136595 | 0.99 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| Hydrochloric Acid SCHEMBL4119582 | 0.99 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| Hydrochloric Acid SCHEMBL4136591 | 0.99 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL5198838 | 0.87 | HTR1A (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL5198894 | 0.86 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL4137188 | 0.86 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL5198903 | 0.86 | TACR1 (0.42) | TACR1SLC9A3TAAR1 | |
| SCHEMBL5227414 | 0.86 | TACR1 (0.42) | TACR1SLC9A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1710240-B1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | SERVIER LAB (FR) | 2007-12-05 | — | — | EP | disclosed |
| EP-1710240-A1 | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | Les Laboratoires Servier (FR) | 2006-10-11 | — | — | EP | disclosed |