SCHEMBL5197859

SCHEMBL5197859

Cc1ccc(S(=O)(=O)Oc2ccc(NC(=O)NS(=O)(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 7/20 0.71
ENPP3 O14638 6/20 0.71
ENPP2 Q13822 5/20 0.71
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
RECQL P46063 1/20 0.60
TP53 P04637 1/20 0.60
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA4 P22748 1/20 0.60
CA6 P23280 1/20 0.60
CA5A P35218 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA13 Q8N1Q1 1/20 0.60
CA14 Q9ULX7 1/20 0.60
LMNA P02545 1/20 0.59
PPARG P37231 1/20 0.57
RAB9A P51151 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5185950 0.94 CA12 (0.67) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL5198399 0.94 CA12 (0.67) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL5185924 0.89 LMNA (0.71) ENPP1ENPP3ENPP2MEN1KMT2A
Ly-181984 SCHEMBL4612056 0.89 RECQL (0.74) MEN1KMT2ARECQLTP53CA12
SCHEMBL6325999 0.88 LMNA (0.73) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL5186603 0.86 LMNA (0.57) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL22187375 0.85 MEN1 (0.78) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL22187256 0.85 ENPP2 (0.67) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL28395439 0.84 LMNA (0.60) ENPP1ENPP3ENPP2MEN1KMT2A
SCHEMBL23141148 0.84 RECQL (0.67) MEN1KMT2ARECQLTP53CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP claimed
US-20050148467-A1 Heat-sensitive recording material JUJO THERMAL OY (FI) 2005-07-07 US claimed