Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197911 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| Hydrochloric Acid SCHEMBL10737660 | 0.99 | SMN1; SMN2 (0.65) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| Hydrochloric Acid SCHEMBL10737671 | 0.99 | SMN1; SMN2 (0.65) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL9070414 | 0.94 | CHRNA1 (0.69) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| Hydrochloric Acid SCHEMBL9088331 | 0.93 | CHRNA1 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL7995471 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL7995469 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL1866150 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL12373561 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 | |
| SCHEMBL1866151 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2CHRNA1CHRNA3CHRNA7CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483052-B1 | Picolinoxides | CIBA GEIGY AG (CH) | 1997-03-12 | — | — | EP | claimed |
| US-4647570-A | Pesticidal novel nitromethylene derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-03-03 | — | — | US | claimed |
| JP-60172976-A | — | — | None | — | — | JP | disclosed |
| EP-1348705-B1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | PRESIDENT OF GIFU UNIVERSITY (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-6875778-B2 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | GIFU UNIVERSITY | 2005-04-05 | — | — | US | disclosed |
| US-20030220305-A1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | GIFU UNIVERSITY | 2003-11-27 | — | — | US | disclosed |
| EP-1348705-A2 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | President of Gifu University (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-6022967-A | 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0154178-B1 | NITROMETHYLENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND INSECTICIDAL, MITICIDAL AND NEMATICIDAL AGENTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4680294-A | Pesticidal novel nitromethylene derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4647570-A | Pesticidal novel nitromethylene derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0154178-A1 | Nitromethylene derivatives, method for their preparation and insecticidal, miticidal and nematicidal agents | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-09-11 | — | — | EP | disclosed |
| JP-S60172976-A | NITROMETHYLENE DERIVATIVE, ITS PREPARATION AND INSECTICIDAL, MITICIDAL AND NEMATOCIDAL AGENT | NIPPON TOKUSHU NOYAKU SEIZO KK | 1985-09-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220305-A1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | KCNH1, KCNH3, KCNH2 | SMN1; SMN2 574/4885CHRNA1 312/4885CHRNA3 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.