Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425871 | 1.00 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5424934 | 1.00 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7412414 | 0.93 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5428125 | 0.93 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5431277 | 0.93 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7441797 | 0.91 | MEN1 (0.67) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7437412 | 0.90 | MEN1 (0.66) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7429331 | 0.89 | MEN1 (0.65) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7432689 | 0.87 | MEN1 (0.77) | MEN1KMT2ACHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL8086894 | 0.82 | KMT2A (1.00) | MEN1KMT2ACHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761507-A1 | PHOSPHODIESTERASE-INHIBITING COMPOUNDS OF THE 2,3-BENZODIAZEPINE TYPE | Greenpharma (FR) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005113517-A1 | PHOSPHODIESTERASE-INHIBITING COMPOUNDS OF THE 2,3-BENZODIAZEPINE TYPE | GREENPHARMA (FR) | 2005-12-01 | — | — | WO | disclosed |