Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.67 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424934 | 0.91 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5425871 | 0.91 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5198155 | 0.91 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7437412 | 0.89 | MEN1 (0.66) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7432689 | 0.86 | MEN1 (0.77) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5431277 | 0.84 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5428125 | 0.84 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7412414 | 0.84 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL14599857 | 0.81 | MEN1 (0.86) | MEN1KMT2ACHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL43522 | 0.81 | KMT2A (1.00) | MEN1KMT2ACHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |