Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431277 | 1.00 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5428125 | 1.00 | MEN1 (0.60) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5424934 | 0.93 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5198155 | 0.93 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5425871 | 0.93 | MEN1 (0.69) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5183272 | 0.87 | KMT2A (0.53) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5198392 | 0.87 | KMT2A (0.53) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL5434678 | 0.87 | KMT2A (0.53) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7441797 | 0.84 | MEN1 (0.67) | MEN1KMT2ACHRM1PDE4APDE4D | |
| SCHEMBL7437412 | 0.83 | MEN1 (0.66) | MEN1KMT2ACHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088096-A1 | COMPOUNDS INHIBITING CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, PREPARATION AND USES THEREOF | NEURO3D (FR) | 2002-11-07 | — | — | WO | claimed |