Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586121 | 0.88 | HSD11B1 (0.41) | TACR1HSD11B1OPRM1 | |
| SCHEMBL3151727 | 0.86 | TACR1 (0.59) | TACR1 | |
| SCHEMBL5380076 | 0.83 | HSD11B1 (0.48) | TACR1HSD11B1CHRM5CHRM1CHRM3 | |
| SCHEMBL9370329 | 0.81 | DPP4 (0.44) | TACR1CHRM1 | |
| SCHEMBL8120644 | 0.81 | DPP4 (0.49) | TACR1CHRM1 | |
| SCHEMBL15861819 | 0.80 | SLC6A4 (0.50) | TACR1CHRM1 | |
| SCHEMBL23089137 | 0.78 | SLC6A9 (0.37) | APP | |
| SCHEMBL2425376 | 0.76 | HSD11B1 (0.58) | TACR1HSD11B1OPRM1KCNA3 | |
| SCHEMBL17886652 | 0.76 | TACR1 (0.53) | TACR1 | |
| SCHEMBL5196781 | 0.75 | OPRL1 (0.40) | CHRM5CHRM1CHRM3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-A2 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006021655-A2 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |