Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603778 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL20797272 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL4753817 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL20457202 | 0.80 | KMT2A (0.54) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL5198293 | 0.80 | KMT2A (0.54) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL22393320 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2APKMGPR119KDM4E | |
| SCHEMBL4977409 | 0.78 | KMT2A (0.49) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL26750160 | 0.78 | KMT2A (0.51) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL30363332 | 0.76 | KMT2A (0.50) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL4737609 | 0.76 | KMT2A (0.50) | ALDH1A1KMT2ATGFBR1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
| US-20090048112-A1 | Novel Herbicides | SYNGENTA LIMITED (GB) | 2009-02-19 | — | — | US | disclosed |
| EP-1885720-A2 | 4-(THIAZOL-2-YLTHIOALKYL)-PYRAZOLES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006123088-A2 | 4- (THIAZOL-2-YLTHIOALKYL) -PYRAZOLES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048112-A1 | Novel Herbicides | HAX1, MTX1, CYP4X1 | ALDH1A1 312/4885KMT2A 135/4885TGFBR1 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.