Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198754 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5198640 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL3178031 | 0.80 | CYSLTR1 (0.60) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5200408 | 0.79 | MAPT (0.51) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5200187 | 0.77 | MEN1 (0.51) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5050181 | 0.74 | CYP1A2 (0.67) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5200552 | 0.74 | MEN1 (0.50) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL5200365 | 0.74 | MEN1 (0.48) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL9508098 | 0.72 | MEN1 (0.58) | MEN1KMT2AMAPTCYP1A2TSHR | |
| SCHEMBL9509183 | 0.72 | MEN1 (0.58) | MEN1KMT2AMAPTCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817300-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006057860-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |