Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3164559 | 0.81 | CYSLTR1 (0.52) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5200187 | 0.75 | MEN1 (0.51) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5050181 | 0.75 | CYP1A2 (0.67) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5198754 | 0.74 | MEN1 (0.54) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5198640 | 0.74 | MEN1 (0.54) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5199044 | 0.74 | MEN1 (0.52) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5200365 | 0.72 | MEN1 (0.48) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5200408 | 0.71 | MAPT (0.51) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL5329236 | 0.69 | CYSLTR2 (0.68) | MEN1TSHRKMT2ACYP1A2MAPT | |
| SCHEMBL4797423 | 0.69 | MEN1 (0.56) | MEN1TSHRKMT2ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817300-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006057860-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |