Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23199896 | 0.84 | LRRK2 (0.53) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL29265627 | 0.82 | LRRK2 (0.51) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL15823740 | 0.82 | LRRK2 (0.51) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL16068661 | 0.82 | LRRK2 (0.51) | LRRK2PIM1BTKKDM4ELMNA | |
| Bromide SCHEMBL3499178 | 0.81 | LRRK2 (0.50) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL10915208 | 0.80 | LRRK2 (0.49) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL19924703 | 0.80 | LRRK2 (0.49) | LRRK2PIM1KDM4ELMNACCR1 | |
| Hydrochloric Acid SCHEMBL26126643 | 0.77 | LRRK2 (0.46) | LRRK2PIM1BTKKDM4ELMNA | |
| SCHEMBL2930858 | 0.76 | ILK (0.49) | LRRK2BTKKDM4ELMNACCR1 | |
| SCHEMBL13516442 | 0.73 | KDM4E (0.45) | LRRK2BTKKDM4ELMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |