Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760744 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL20543582 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL5197981 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL1474017 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL15198 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8TDP1 | |
| SCHEMBL1024017 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| Methoxymethane SCHEMBL28668345 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC8TRPA1 | |
| Hydrogen Sulfide SCHEMBL29029008 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL2556558 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 | |
| SCHEMBL13048617 | 0.71 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC8CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481981-B1 | Styrene hypophosphite adduct, preparation thereof and use | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1481981-A2 | Styrene hypophosphite adduct, preparation thereof and use | Clariant GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |