Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTSA | P10619 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.49 |
| ▸ | ITGAV | P06756 | 9/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199829 | 0.86 | ADORA3 (0.55) | POLBSMN1; SMN2CTSAITGB3ITGAV | |
| SCHEMBL5202002 | 0.82 | CTSA (0.46) | CTSAITGB3ITGAV | |
| SCHEMBL4889119 | 0.77 | POLB (0.63) | POLBSMN1; SMN2ITGB3TNFKMT2A | |
| SCHEMBL4875725 | 0.77 | POLB (0.63) | POLBSMN1; SMN2ITGB3TNFKMT2A | |
| SCHEMBL4875740 | 0.77 | POLB (0.63) | POLBSMN1; SMN2ITGB3TNFKMT2A | |
| SCHEMBL4889020 | 0.76 | POLB (0.62) | POLBSMN1; SMN2TNFKMT2A | |
| SCHEMBL4889095 | 0.76 | POLB (0.62) | POLBSMN1; SMN2TNFKMT2A | |
| SCHEMBL4889036 | 0.76 | POLB (0.62) | POLBSMN1; SMN2TNFKMT2A | |
| SCHEMBL29157116 | 0.76 | FFAR1 (0.49) | POLBSMN1; SMN2CTSAKMT2AFFAR1 | |
| SCHEMBL2674709 | 0.75 | FPR2 (0.57) | SMN1; SMN2ITGB3ITGAVKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576179-A4 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2007-06-06 | — | — | EP | disclosed |
| EP-1576179-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004050895-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2004-06-17 | — | — | WO | disclosed |