Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504747 | 0.82 | HDAC3 (0.54) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL400890 | 0.79 | RAB9A (0.77) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL7504363 | 0.79 | RAB9A (0.59) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL12324391 | 0.77 | RAB9A (0.82) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL2897981 | 0.76 | RAB9A (0.65) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL14045090 | 0.75 | RAB9A (0.59) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL6960403 | 0.74 | RAB9A (0.63) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL3724445 | 0.73 | RAB9A (0.68) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL28875360 | 0.73 | SMN1; SMN2 (0.71) | RAB9ANPC1CTDSP1POLBKDM4E | |
| SCHEMBL31167631 | 0.73 | SMN1; SMN2 (0.61) | RAB9ANPC1POLBKDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163245-B2 | (THIO) PHOSPHORYL TRIAMIDES FOR REGULATING THE ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1163245-B1 | (THIO) PHOSPHORYL TRIAMIDES FOR REGULATING THE ENZYMATIC UREA HYDROLYSIS | PIESTERITZ STICKSTOFF (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-1163245-A1 | (THIO) PHOSPHORYL TRIAMIDES FOR REGULATING THE ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000058317-A1 | (THIO) PHOSPHORYL TRIAMIDES FOR REGULATING THE ENZYMATIC UREA HYDROLYSIS | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2000-10-05 | — | — | WO | disclosed |