SCHEMBL400890

SCHEMBL400890

O=C(NNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.77
NPC1 O15118 5/20 0.77
CTDSP1 Q9GZU7 2/20 0.77
KDM4E B2RXH2 2/20 0.71
POLB P06746 2/20 0.71
PTGS2 P35354 1/20 0.70
HDAC3 O15379 1/20 0.67
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
IDO1 P14902 1/20 0.67
ALOX15 P16050 1/20 0.67
HDAC1 Q13547 1/20 0.67
CA9 Q16790 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC2 Q92769 1/20 0.67
HSD17B10 Q99714 1/20 0.67
HDAC8 Q9BY41 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
NCOR2 Q9Y618 1/20 0.67
SMN1; SMN2 Q16637 4/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12324391 0.97 RAB9A (0.82) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL28875360 0.92 SMN1; SMN2 (0.71) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL3724445 0.92 RAB9A (0.68) RAB9ANPC1CTDSP1KDM4EPOLB
Malonic Acid SCHEMBL30274338 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL2897981 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL6963750 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL10309466 0.90 SMN1; SMN2 (0.74) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL16438824 0.89 HDAC3 (0.68) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL6967578 0.88 RAB9A (0.63) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL6960403 0.88 RAB9A (0.63) RAB9ANPC1CTDSP1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428229-B1 CURABLE RESIN COMPOSITION, FUEL CELL, AND SEALING METHOD THREE BOND CO LTD (JP) 2022-08-17 EP claimed
US-10800952-B2 Curable resin composition, fuel cell, and sealing method THREEBOND CO., LTD. (JP) 2020-10-13 US claimed
EP-1928844-A2 BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE Amgen, Inc (US) 2008-06-11 EP claimed
WO-2007022380-A2 BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2007-02-22 WO claimed
EP-1135363-B1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES GREAT LAKES CHEMICAL EUROP (CH) 2003-09-24 EP claimed
US-6444848-B1 REACTING HYDRAZINE WITH ACID CHLORIDE GREAT LAKES CHEMICAL (EUROPE) GMBH (DE) 2002-09-03 US claimed
EP-1135363-A1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES Great Lakes Chemical (Europe) GmbH (CH) 2001-09-26 EP claimed
WO-2000034227-A1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-06-15 WO claimed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP claimed
US-4371602-A Photosensitive printing plate TOKYO OHKA KOGYO CO., LTD. (JP) 1983-02-01 US claimed
JP-8020580-A None JP disclosed
US-20260138359-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES DOW SILICONES CORP (US) 2026-05-21 US disclosed
US-20260109818-A1 LIQUID SILICONE RUBBER COMPOSITION DOW SILICONES CORP (US) 2026-04-23 US disclosed
US-20260098144-A1 RESIN COMPOSITION, FILM WITH RESIN, PREPREG, SHEET OF METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2026-04-09 US disclosed
EP-4590759-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES Dow Silicones Corporation (US) 2025-07-30 EP disclosed
US-4338244-A HEAT AND OXIDATION RESISTANT POLYMERS SANDOZ LTD. (CH) 1982-07-06 US disclosed
US-4325863-A POLYMERS SANDOZ LTD. (CH) 1982-04-20 US disclosed
US-4052362-A N-CINNAMOYL-N'-ACYLHYDRAZINES UBE INDUSTRIES, LTD. (JA) 1977-10-04 US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109818-A1 LIQUID SILICONE RUBBER COMPOSITION MCM5, H1-5, HNRNPH3 RAB9A 3232/4885NPC1 2852/4885CTDSP1 876/4885
US-20260098144-A1 RESIN COMPOSITION, FILM WITH RESIN, PREPREG, SHEET OF METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD ATP1A4, ATP4B, ATP1B3 RAB9A 2144/4885NPC1 2834/4885CTDSP1 2716/4885
US-20260138359-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES MLST8, MCM7, RPL23 RAB9A 4663/4885NPC1 4346/4885CTDSP1 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.