SCHEMBL400890

SCHEMBL400890

O=C(NNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 6/20 0.77
▸ NPC1 O15118 5/20 0.77
▸ CTDSP1 Q9GZU7 2/20 0.77
▸ KDM4E B2RXH2 2/20 0.71
▸ POLB P06746 2/20 0.71
▸ PTGS2 P35354 1/20 0.70
▸ HDAC3 O15379 1/20 0.67
▸ CA12 O43570 1/20 0.67
▸ CA1 P00915 1/20 0.67
▸ IDO1 P14902 1/20 0.67
▸ ALOX15 P16050 1/20 0.67
▸ HDAC1 Q13547 1/20 0.67
▸ CA9 Q16790 1/20 0.67
▸ HDAC7 Q8WUI4 1/20 0.67
▸ HDAC2 Q92769 1/20 0.67
▸ HSD17B10 Q99714 1/20 0.67
▸ HDAC8 Q9BY41 1/20 0.67
▸ HDAC6 Q9UBN7 1/20 0.67
▸ NCOR2 Q9Y618 1/20 0.67
▸ SMN1; SMN2 Q16637 4/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12324391 0.97 RAB9A (0.82) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL28875360 0.92 SMN1; SMN2 (0.71) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL3724445 0.92 RAB9A (0.68) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL10309466 0.90 SMN1; SMN2 (0.74) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL2897981 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
Malonic Acid SCHEMBL30274338 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL6963750 0.90 RAB9A (0.65) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL16438824 0.89 HDAC3 (0.68) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL13454574 0.88 RAB9A (0.63) RAB9ANPC1CTDSP1KDM4EPOLB
SCHEMBL11298577 0.88 RAB9A (0.75) RAB9ANPC1CTDSP1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428229-B1 CURABLE RESIN COMPOSITION, FUEL CELL, AND SEALING METHOD THREE BOND CO LTD (JP) 2022-08-17 — — EP claimed
US-10800952-B2 Curable resin composition, fuel cell, and sealing method THREEBOND CO., LTD. (JP) 2020-10-13 — — US claimed
EP-1928844-A2 BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE Amgen, Inc (US) 2008-06-11 — — EP claimed
WO-2007022380-A2 BIS-ARYL AMIDE COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2007-02-22 — — WO claimed
EP-1135363-B1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES GREAT LAKES CHEMICAL EUROP (CH) 2003-09-24 — — EP claimed
US-6444848-B1 REACTING HYDRAZINE WITH ACID CHLORIDE GREAT LAKES CHEMICAL (EUROPE) GMBH (DE) 2002-09-03 — — US claimed
EP-1135363-A1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES Great Lakes Chemical (Europe) GmbH (CH) 2001-09-26 — — EP claimed
WO-2000034227-A1 PROCESS FOR THE PREPARATION OF SYMMETRICAL DIACYLHYDRAZINES GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-06-15 — — WO claimed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 — — EP claimed
US-4371602-A Photosensitive printing plate TOKYO OHKA KOGYO CO., LTD. (JP) 1983-02-01 — — US claimed
JP-8020580-A — — None — — JP disclosed
US-20260138359-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES DOW SILICONES CORP (US) 2026-05-21 — — US disclosed
US-20260109818-A1 LIQUID SILICONE RUBBER COMPOSITION DOW SILICONES CORP (US) 2026-04-23 — — US disclosed
US-20260098144-A1 RESIN COMPOSITION, FILM WITH RESIN, PREPREG, SHEET OF METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2026-04-09 — — US disclosed
EP-4590759-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES Dow Silicones Corporation (US) 2025-07-30 — — EP disclosed
US-4338244-A HEAT AND OXIDATION RESISTANT POLYMERS SANDOZ LTD. (CH) 1982-07-06 — — US disclosed
US-4325863-A POLYMERS SANDOZ LTD. (CH) 1982-04-20 — — US disclosed
US-4052362-A N-CINNAMOYL-N'-ACYLHYDRAZINES UBE INDUSTRIES, LTD. (JA) 1977-10-04 — — US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 — — US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109818-A1 LIQUID SILICONE RUBBER COMPOSITION MCM5, H1-5, HNRNPH3 RAB9A 3232/4885NPC1 2852/4885CTDSP1 876/4885
US-20260098144-A1 RESIN COMPOSITION, FILM WITH RESIN, PREPREG, SHEET OF METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD ATP1A4, ATP4B, ATP1B3 RAB9A 2144/4885NPC1 2834/4885CTDSP1 2716/4885
US-20260138359-A1 SILICONE-THERMOPLASTIC COMPOSITE ARTICLES MLST8, MCM7, RPL23 RAB9A 4663/4885NPC1 4346/4885CTDSP1 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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