Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6503554 | 0.98 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRCA2CHKA | |
| SCHEMBL6543859 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL1127702 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL5633342 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL10002524 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL30562291 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHTTPOLB | |
| Hydrochloric Acid SCHEMBL6544280 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL8177031 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL6544388 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TP53TSHRHTTPOLB | |
| SCHEMBL6730674 | 0.82 | CA2 (0.41) | ALDH1A1TP53CA2CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422160-C | Morpholine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2008-10-01 | — | — | CN | disclosed |
| EP-1150970-B1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI AVENTIS (FR) | 2007-08-22 | — | — | EP | disclosed |
| US-20050054637-A1 | Substituted piperazine cyclohexane carboxilic acid amides and the use thereof | PASCAL ENGINEERING CORPORATION (JP) | 2005-03-10 | — | — | US | disclosed |
| US-20050054637-A1 | Substituted piperazine cyclohexane carboxilic acid amides and the use thereof | PASCAL ENGINEERING CORPORATION (JP) | 2005-03-10 | — | — | US | disclosed |
| US-20050054637-A1 | Substituted piperazine cyclohexane carboxilic acid amides and the use thereof | PASCAL ENGINEERING CORPORATION (JP) | 2005-03-10 | — | — | US | disclosed |
| EP-1165528-B1 | NOVEL MORPHOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID DERIVATIVES | SANOFI SYNTHELABO (FR) | 2004-09-01 | — | — | EP | disclosed |
| EP-1436273-A1 | SUBSTITUTED PIPERAZINE CYCLOHEXANE CARBOXILIC ACID AMIDES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033484-A1 | SUBSTITUTED PIPERAZINE CYCLOHEXANE CARBOXILIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-04-24 | — | — | WO | disclosed |
| EP-1165528-A1 | NOVEL MORPHOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2002-01-02 | — | — | EP | disclosed |
| EP-1150970-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000058292-A1 | NOVEL MORPHOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000047572-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054637-A1 | Substituted piperazine cyclohexane carboxilic acid amides and the use thereof | AADAC, HCAR2, EGLN2 | ALDH1A1 472/4885TP53 4598/4885TSHR 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.