Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199090 | 0.86 | UPP1 (0.32) | ALDH1A1L3MBTL1TDP1UPP1 | |
| SCHEMBL5198843 | 0.78 | UPP1 (0.35) | ALDH1A1UPP1 | |
| SCHEMBL2793543 | 0.76 | UPP1 (0.41) | RECQLBLMUPP1 | |
| SCHEMBL23752310 | 0.73 | ALDH1A1 (0.34) | ALDH1A1TDP1 | |
| SCHEMBL7258543 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL7260757 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1POLBUPP1 | |
| SCHEMBL6302823 | 0.71 | UPP1 (0.34) | ALDH1A1UPP1 | |
| SCHEMBL7255129 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7258815 | 0.69 | MEN1 (0.33) | ALDH1A1POLB | |
| SCHEMBL7756562 | 0.69 | TSHR (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355887-B1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | UNIV GENEVE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-6911450-B1 | Pyrimidine acyclonucleoside derivatives, preparation method and use thereof | UNIVERSITE DE GENEVE (CH) | 2005-06-28 | — | — | US | disclosed |