Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254857 | 0.93 | ALDH1A1 (0.37) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7255113 | 0.86 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL7255109 | 0.86 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL7258543 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7255129 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23752310 | 0.79 | ALDH1A1 (0.34) | ALDH1A1KMT2A | |
| SCHEMBL7756553 | 0.79 | TSHR (0.37) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7756562 | 0.79 | TSHR (0.37) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7255123 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2ASMN1; SMN2HPGD | |
| SCHEMBL7258815 | 0.78 | MEN1 (0.33) | ALDH1A1KDM4EKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |