Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | RIPK3 | Q9Y572 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402128 | 0.90 | DYRK1A (0.49) | ENPP3ENPP1ENPP2CLK1SNCA | |
| SCHEMBL4396704 | 0.87 | CLK1 (0.51) | ENPP3ENPP1ENPP2CLK1DYRK1A | |
| SCHEMBL4394769 | 0.84 | CLK1 (0.56) | ENPP3ENPP1ENPP2CLK1DYRK1A | |
| SCHEMBL4397027 | 0.83 | ENPP3 (0.53) | ENPP3ENPP1ENPP2CLK1SNCA | |
| SCHEMBL4399622 | 0.82 | ALDH1A1 (0.51) | SNCADYRK1ANPC1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4397600 | 0.81 | ALDH1A1 (0.51) | SNCADYRK1ANPC1ALDH1A1HPGD | |
| SCHEMBL4397038 | 0.81 | ALDH1A1 (0.43) | NPC1ALDH1A1SMN1; SMN2HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL4397033 | 0.81 | ALDH1A1 (0.42) | NPC1ALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4404654 | 0.80 | ENPP3 (0.62) | ENPP3ENPP1ENPP2CLK1NPC1 | |
| SCHEMBL4402171 | 0.80 | ENPP3 (0.56) | ENPP3ENPP1ENPP2CLK1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745044-A2 | BENZOTHIAZOLE DERIVATIVES HAVING CDK MODULATING ACTIVITY AND USE THEREOF AS ANTICANCER AGENTS | Aventis Pharma S.A. (FR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005097787-A2 | NOVEL BENZOTHIAZOLES AND THE USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA S.A. (FR) | 2005-10-20 | — | — | WO | disclosed |