Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559459 | 0.83 | CTRB1 (0.51) | KMT2AALDH1A1CTSSCTSK | |
| SCHEMBL4923623 | 0.81 | CTSS (0.54) | LMNACTSSCTSK | |
| SCHEMBL14034476 | 0.80 | MME (0.48) | PPARGPPARAKMT2AALDH1A1MEN1 | |
| SCHEMBL6407838 | 0.75 | CNR2 (0.45) | KMT2AALDH1A1MEN1 | |
| SCHEMBL6407833 | 0.75 | CNR2 (0.45) | KMT2AALDH1A1MEN1 | |
| SCHEMBL5562553 | 0.71 | CTRB1 (0.52) | KMT2AALDH1A1CTSSCTSK | |
| SCHEMBL4917131 | 0.69 | CTSS (0.55) | CTSSCTSK | |
| SCHEMBL4917142 | 0.69 | CTSS (0.55) | CTSSCTSK | |
| SCHEMBL5177986 | 0.69 | NOTUM (0.47) | KMT2AALDH1A1MEN1LMNAGAA | |
| SCHEMBL28807054 | 0.68 | PPARG (0.51) | PPARGPPARAKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858846-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097175-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2006-09-21 | — | — | WO | disclosed |