Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 8/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853070 | 0.93 | HTR2C (0.38) | HTR2CSOS1KDM1A | |
| SCHEMBL4842921 | 0.90 | HTR2C (0.38) | HTR2CSOS1KDM1APIM1 | |
| SCHEMBL4841841 | 0.84 | SOS1 (0.42) | HTR2CSOS1KDM1APIM1 | |
| SCHEMBL68342 | 0.82 | PIM1 (0.41) | HTR2CPIM1 | |
| SCHEMBL4841972 | 0.74 | SOS1 (0.44) | HTR2CSOS1KDM1APIM1 | |
| SCHEMBL68028 | 0.70 | ACVR1 (0.42) | — | |
| SCHEMBL4847436 | 0.65 | HTR2C (0.36) | HTR2CSOS1PIM1 | |
| SCHEMBL68112 | 0.65 | DGAT1 (0.41) | — | |
| SCHEMBL5213310 | 0.63 | DGAT1 (0.37) | — | |
| SCHEMBL23781131 | 0.63 | DGAT1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802605-A1 | IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Amgen, Inc (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044527-A1 | IMIDAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |