Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983249 | 0.73 | BACE1 (0.56) | BACE1NOS1ENPP3ENPP1CA12 | |
| SCHEMBL558480 | 0.71 | ALDH1A1 (0.46) | LMNA | |
| SCHEMBL10476670 | 0.69 | BACE1 (0.47) | BACE1NOS1ENPP3ENPP1CA12 | |
| SCHEMBL6477443 | 0.67 | BACE1 (0.44) | BACE1NOS1ENPP3ENPP1CA12 | |
| SCHEMBL28573272 | 0.65 | ALDH1A1 (0.56) | BACE1LMNA | |
| SCHEMBL3050683 | 0.64 | BACE1 (0.50) | BACE1NOS1SMN1; SMN2 | |
| SCHEMBL7547167 | 0.64 | BACE1 (0.46) | BACE1LMNA | |
| SCHEMBL3558158 | 0.64 | BACE1 (0.41) | BACE1NOS1LMNASMN1; SMN2 | |
| SCHEMBL2850764 | 0.64 | PSMD14 (0.65) | BACE1 | |
| SCHEMBL3713340 | 0.64 | BACE1 (0.41) | BACE1NOS1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817309-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | Syngeta Participations AG (CH) | 2007-08-15 | — | — | EP | claimed |
| WO-2006058700-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-08 | — | — | WO | claimed |