Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.47 |
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | CCND1 | P24385 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089484 | 0.84 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL8124145 | 0.81 | ADORA1 (0.65) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL5202853 | 0.79 | MEN1 (0.50) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL19926114 | 0.79 | CDK4 (0.53) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL5199692 | 0.79 | MAPT (0.51) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL7114450 | 0.77 | ADORA2A (0.46) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL5236193 | 0.75 | ALDH1A1 (0.68) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL1802347 | 0.75 | DYRK1A (0.48) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL13516427 | 0.74 | MAPT (0.50) | KMT2AMEN1MAPTKDM4EDYRK1A | |
| SCHEMBL28067319 | 0.74 | MAPT (0.50) | KMT2AMEN1MAPTKDM4EDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |