Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775849 | 0.81 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL5201367 | 0.79 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL5236193 | 0.79 | ALDH1A1 (0.68) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8914694 | 0.78 | ADORA1 (0.54) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7107364 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| Sulfuric Acid SCHEMBL5402716 | 0.74 | FGFR1 (0.42) | SMN1; SMN2ALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL1802385 | 0.74 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL842957 | 0.72 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL2918159 | 0.72 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL17054307 | 0.71 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |