Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836970 | 0.79 | HTR3E (0.65) | IDO1MAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL843513 | 0.79 | CTBP2 (0.57) | CYP1A2LMNASMN1; SMN2PMP22HTR3E | |
| SCHEMBL12246382 | 0.79 | CTBP2 (0.57) | CYP1A2LMNASMN1; SMN2PMP22HTR3E | |
| SCHEMBL17115029 | 0.79 | HTR3E (0.65) | IDO1MAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL27375402 | 0.78 | SIGMAR1 (0.44) | LMNASMN1; SMN2HTR3EHTR3BHTR3A | |
| SCHEMBL100935 | 0.78 | TAAR1 (0.50) | IDO1MAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL100936 | 0.78 | TAAR1 (0.50) | IDO1MAPK8HTR3EHTR3BHTR3A | |
| SCHEMBL1580469 | 0.78 | CTBP2 (0.58) | LMNASMN1; SMN2IDO1MAPK8HTR3E | |
| SCHEMBL1580471 | 0.78 | CTBP2 (0.58) | LMNASMN1; SMN2IDO1MAPK8HTR3E | |
| SCHEMBL29492946 | 0.77 | CYP1A2 (0.55) | HIF1ACYP1A2CYP2D6CYP2C19THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817301-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006057870-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |