Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909158 | 0.90 | SLC6A9 (0.85) | SLC6A9KCNH2GPR55 | |
| SCHEMBL5462433 | 0.85 | SLC6A9 (0.77) | SLC6A9GPR55 | |
| SCHEMBL4901304 | 0.85 | SLC6A9 (1.00) | SLC6A9KCNH2GPR55 | |
| SCHEMBL6023463 | 0.84 | SLC6A9 (0.61) | SLC6A9KCNH2GPR55 | |
| SCHEMBL6011913 | 0.84 | SLC6A9 (0.61) | SLC6A9KCNH2GPR55 | |
| SCHEMBL6026998 | 0.84 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL4906491 | 0.80 | SLC6A9 (0.67) | SLC6A9KCNH2GPR55 | |
| SCHEMBL6026824 | 0.79 | SLC6A9 (0.64) | SLC6A9KCNH2 | |
| SCHEMBL6027426 | 0.79 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL4908726 | 0.79 | SLC6A9 (0.72) | SLC6A9KCNH2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836178-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F. Hoffmann-Roche AG (CH) | 2007-09-26 | — | — | EP | claimed |
| WO-2006072435-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-07-13 | — | — | WO | claimed |
| EP-1836178-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F. Hoffmann-Roche AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006072435-A1 | SULFANYL SUBSTITUTED PHENYL METHANONES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-07-13 | — | — | WO | disclosed |