Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462433 | 0.89 | SLC6A9 (0.77) | SLC6A9GPR55 | |
| SCHEMBL6011913 | 0.89 | SLC6A9 (0.61) | SLC6A9GPR55KCNH2 | |
| SCHEMBL6026998 | 0.84 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL5201493 | 0.84 | SLC6A9 (0.73) | SLC6A9GPR55KCNH2 | |
| SCHEMBL3927542 | 0.83 | SLC6A9 (0.75) | SLC6A9GPR55 | |
| SCHEMBL6027426 | 0.83 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL6026824 | 0.83 | SLC6A9 (0.64) | SLC6A9KCNH2 | |
| SCHEMBL27664328 | 0.83 | SLC6A9 (0.59) | SLC6A9GPR55KCNH2 | |
| SCHEMBL6011779 | 0.82 | SLC6A9 (0.58) | SLC6A9GPR55 | |
| SCHEMBL6011862 | 0.82 | SLC6A9 (0.58) | SLC6A9GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663232-A1 | 1-(2-AMINO-BENZOYL)-PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023260-A1 | 1- (2-AMINO-BENZOL) -PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-17 | — | — | WO | disclosed |