Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205217 | 0.91 | — | — | |
| SCHEMBL5205434 | 0.86 | PTGS2 (0.54) | PTGS2PTGS1PDPK1CA12CA1 | |
| SCHEMBL5273552 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL5207362 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL5205315 | 0.78 | PTGS1 (0.51) | PTGS2PTGS1PDPK1CA12CA1 | |
| SCHEMBL5203292 | 0.78 | PTGS2 (0.40) | PTGS2PTGS1CA2CA4 | |
| SCHEMBL5865384 | 0.77 | — | — | |
| SCHEMBL28753554 | 0.77 | — | — | |
| SCHEMBL5204508 | 0.77 | KEAP1 (0.45) | PTGS2PTGS1PDPK1CA12CA1 | |
| SCHEMBL5239915 | 0.77 | PTGS2 (0.50) | PTGS2PTGS1PDPK1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688554-A | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2005-10-26 | — | — | CN | claimed |
| CN-101012203-B | 1,2,4-triazol derivatives, method for preparing the same | CJ CORP | 2011-02-16 | — | — | CN | disclosed |
| CN-100357277-C | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-101012203-A | 1,2,4-triazol derivatives, method for preparing the same | CJ CORP (KR) | 2007-08-08 | — | — | CN | disclosed |
| EP-1539718-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORP (KR) | 2007-08-01 | — | — | EP | disclosed |
| US-7019144-B2 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2006-03-28 | — | — | US | disclosed |
| CN-1688554-A | 1,2, 4-triazole derivatives, process for preparing the same and pharmaceutical composition containing the same | CJ CORP (KR) | 2005-10-26 | — | — | CN | disclosed |
| EP-1539718-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-06-15 | — | — | EP | disclosed |
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2005-04-07 | — | — | US | disclosed |
| WO-2004014878-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075507-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CYP4B1, CYP3A5, CYP7A1 | PTGS2 1769/4885PTGS1 523/4885PDPK1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.