Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.36 |
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 2/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203314 | 0.94 | NR3C1 (0.40) | NR3C1IGF1RNR3C2PGR | |
| SCHEMBL5203059 | 0.92 | NR3C1 (0.35) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL4821088 | 0.88 | MRGPRX4 (0.40) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL4821113 | 0.88 | MRGPRX4 (0.40) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL4821100 | 0.88 | MRGPRX4 (0.40) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL5203194 | 0.87 | NR3C1 (0.39) | NR3C1IGF1RNR3C2PGR | |
| SCHEMBL5203051 | 0.87 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4820381 | 0.87 | NR3C1 (0.36) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL4820369 | 0.87 | NR3C1 (0.36) | NR3C1IGF1RCYP19A1NR3C2PGR | |
| SCHEMBL4820376 | 0.87 | NR3C1 (0.36) | NR3C1IGF1RCYP19A1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |