Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201683 | 0.94 | NR3C1 (0.36) | NR3C1NR3C2PGRIGF1R | |
| SCHEMBL5203194 | 0.93 | NR3C1 (0.39) | NR3C1NR3C2PGRIGF1R | |
| SCHEMBL5203051 | 0.92 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4823435 | 0.88 | MRGPRX4 (0.43) | NR3C1NR3C2PGRIGF1RMRGPRX4 | |
| SCHEMBL4823447 | 0.88 | MRGPRX4 (0.43) | NR3C1NR3C2PGRIGF1RMRGPRX4 | |
| SCHEMBL4823443 | 0.88 | MRGPRX4 (0.43) | NR3C1NR3C2PGRIGF1RMRGPRX4 | |
| SCHEMBL5203059 | 0.86 | NR3C1 (0.35) | NR3C1NR3C2PGRIGF1R | |
| SCHEMBL4825973 | 0.85 | NR3C1 (0.40) | NR3C1NR3C2PGRIGF1RMRGPRX4 | |
| SCHEMBL4825978 | 0.85 | NR3C1 (0.40) | NR3C1NR3C2PGRIGF1RMRGPRX4 | |
| SCHEMBL4825975 | 0.85 | NR3C1 (0.40) | NR3C1NR3C2PGRIGF1RMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |