Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205440 | 0.91 | MAPK14 (0.58) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL5205465 | 0.89 | MAPK14 (0.50) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL5205115 | 0.88 | MAPK14 (0.57) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL5201020 | 0.88 | MAPK14 (0.56) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL5200970 | 0.84 | MAPK14 (0.52) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL5203602 | 0.84 | MAPK14 (0.51) | MAPK14CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5207414 | 0.84 | MAPK14 (0.52) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL21133758 | 0.81 | MAPK14 (0.58) | MAPK14CYP2C9CYP2C19MLNRCYP3A4 | |
| SCHEMBL14454037 | 0.81 | MAPK14 (0.58) | MAPK14CYP2C9CYP2C19 | |
| SCHEMBL5201216 | 0.81 | MAPK14 (0.51) | MAPK14CYP2C9CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178983-B1 | INDOLE-TYPE DERIVATIVES AS INHIBITORS OF P38 KINASE | SCIOS INC (US) | 2007-10-24 | — | — | EP | claimed |