Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.52 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524876 | 0.97 | KIF11 (0.54) | KIF11KCNN4TAAR1KCNH2CYP3A4 | |
| SCHEMBL28840464 | 0.85 | KIF11 (0.44) | KIF11KCNN4TAAR1 | |
| SCHEMBL3630705 | 0.83 | KIF11 (0.68) | KIF11KCNN4TAAR1KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6574459 | 0.82 | HTR2A (0.54) | KIF11TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| SCHEMBL28472455 | 0.81 | KIF11 (0.59) | KIF11KCNN4TAAR1KCNH2CYP3A4 | |
| SCHEMBL3742639 | 0.80 | KIF11 (0.41) | KIF11KCNH2CYP3A4CYP2D6 | |
| SCHEMBL29674396 | 0.79 | KIF11 (0.57) | KIF11KCNN4TAAR1KCNH2CYP3A4 | |
| SCHEMBL902585 | 0.79 | KIF11 (0.57) | KIF11KCNN4TAAR1KCNH2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL7564407 | 0.79 | TAAR1 (0.54) | KIF11KCNN4TAAR1LOXL2 | |
| SCHEMBL9722974 | 0.79 | LTA4H (0.53) | KIF11TAAR1KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651657-B1 | BIPHOSPHINE RUTHENIUM COMPLEXES WITH CHIRAL DIAMINE LIGANDS AS CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2007-08-22 | — | — | EP | claimed |