Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053167 | 0.83 | HDAC1 (0.68) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2808918 | 0.81 | KMT2A (0.49) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL6150938 | 0.80 | KDM4E (0.56) | MAPK14MAPTMEN1KMT2AGAA | |
| SCHEMBL5206028 | 0.80 | MAPK1 (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL5206034 | 0.80 | MAPK1 (0.57) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL5203690 | 0.79 | FFAR1 (0.47) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL8773482 | 0.77 | MEN1 (0.69) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL11403590 | 0.77 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL335254 | 0.76 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2340705 | 0.75 | MEN1 (0.46) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |