Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206034 | 1.00 | MAPK1 (0.57) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL5201785 | 0.80 | MAPK13 (0.54) | TDP1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL1408481 | 0.79 | MAPK1 (0.67) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL27226881 | 0.77 | MAPT (0.69) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL27898835 | 0.77 | MAPK1 (0.73) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL3909830 | 0.77 | MAPK1 (0.73) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL15082040 | 0.77 | L3MBTL1 (0.68) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL5202945 | 0.77 | ALDH1A1 (0.48) | TDP1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL13939148 | 0.77 | ALDH1A1 (0.63) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 | |
| SCHEMBL6177114 | 0.77 | MAPK1 (0.63) | MAPK1TDP1ALDH1A1CASP7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |