Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.63 |
| ▸ | GRK6 | P43250 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279692 | 1.00 | NR1H2 (0.63) | NR1H2NR1H3GRK6NPC1LMNA | |
| SCHEMBL17280065 | 0.90 | NR1H2 (0.57) | NR1H2NR1H3GRK6NPC1LMNA | |
| SCHEMBL17280022 | 0.87 | NR1H2 (0.57) | NR1H2NR1H3GRK6NPC1LMNA | |
| SCHEMBL17279698 | 0.84 | NR1H2 (0.69) | NR1H2NR1H3NPC1LMNARAB9A | |
| SCHEMBL5209232 | 0.83 | NR1H2 (0.73) | NR1H2NR1H3NPC1LMNARAB9A | |
| SCHEMBL16151160 | 0.83 | GRK6 (0.53) | GRK6NPC1LMNARAB9ADGAT1 | |
| SCHEMBL17280027 | 0.82 | NR1H2 (0.54) | NR1H2NR1H3GRK6NPC1LMNA | |
| SCHEMBL17574086 | 0.81 | NR1H2 (0.96) | NR1H2NR1H3NPC1LMNARAB9A | |
| SCHEMBL26109969 | 0.81 | NR1H2 (0.96) | NR1H2NR1H3NPC1LMNARAB9A | |
| SCHEMBL17280023 | 0.81 | NR1H2 (0.52) | NR1H2NR1H3GRK6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | NR1H2 10/4885NR1H3 11/4885GRK6 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.