Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5203271 | 0.93 | ALDH1A1 (0.34) | KDM4ELMNA | |
| Trifluoroacetic Acid SCHEMBL5208456 | 0.93 | TSPO (0.40) | KDM4ELMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5205925 | 0.92 | PSMB8 (0.33) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5202498 | 0.91 | EPHX2 (0.38) | EPHX2MAP2K7KDM4ESCN9ATPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5205478 | 0.91 | KMT2A (0.33) | KDM4ETPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5201857 | 0.90 | HCRTR2 (0.34) | KDM4ELMNATPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5202054 | 0.89 | TSPO (0.39) | EPHX2TPSAB1PPARG | |
| Trifluoroacetic Acid SCHEMBL5207856 | 0.89 | KMT2A (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL5205650 | 0.87 | TAOK1 (0.38) | EPHX2MAP2K7KDM4ETPSAB1P2RX4 | |
| Trifluoroacetic Acid SCHEMBL5205759 | 0.87 | TAOK1 (0.36) | EPHX2KDM4ELMNASMN1; SMN2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |