Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16927398 | 0.83 | NR4A2 (0.46) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL312058 | 0.78 | ESR1 (0.57) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL7323586 | 0.76 | KDM4E (0.51) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL14261867 | 0.74 | ESR1 (0.72) | ESR1ESR2SMN1; SMN2HPGDFFAR4 | |
| SCHEMBL28906146 | 0.74 | KDM4E (0.48) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL6439681 | 0.74 | MAOA (0.48) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL29940757 | 0.74 | KDM4E (0.48) | ESR1ESR2MAOAKDM4EALDH1A1 | |
| SCHEMBL28543077 | 0.73 | ESR1 (0.54) | ESR1ESR2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL6711107 | 0.73 | ESR1 (0.50) | ESR1ESR2MAOACYP3A4SMN1; SMN2 | |
| SCHEMBL9035687 | 0.72 | ESR1 (0.53) | ESR1ESR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176252-B2 | Solid melt blended phosphite composites | DOVER CHEMICAL CORPORATION (US) | 2007-02-13 | — | — | US | disclosed |
| US-20040164279-A1 | Solid melt blended phosphite composites | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040164279-A1 | Solid melt blended phosphite composites | PHOSPHO1, MTAP, INPPL1 | ESR1 3297/4885ESR2 3960/4885MAOA 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.