Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202274 | 0.76 | ESR1 (0.50) | KDM4ECASP1CASP7ALDH1A1HPGD | |
| SCHEMBL16927398 | 0.75 | NR4A2 (0.46) | KDM4ECASP1CASP7MEN1KMT2A | |
| SCHEMBL11553711 | 0.71 | PLK1 (0.44) | KDM4EMEN1KMT2ATSHRHTT | |
| SCHEMBL312058 | 0.70 | ESR1 (0.57) | KDM4EMEN1KMT2AUSP2GAA | |
| SCHEMBL29549526 | 0.70 | KDM4E (0.52) | KDM4ECASP1CASP7MEN1KMT2A | |
| SCHEMBL5246464 | 0.68 | KDM4E (1.00) | KDM4ECASP1CASP7MEN1KMT2A | |
| SCHEMBL28256199 | 0.68 | MEN1 (0.69) | KDM4ECASP1CASP7MEN1KMT2A | |
| SCHEMBL28257700 | 0.68 | MEN1 (0.69) | KDM4ECASP1CASP7MEN1KMT2A | |
| SCHEMBL6439681 | 0.67 | MAOA (0.48) | KDM4ECASP1CASP7GAAALDH1A1 | |
| SCHEMBL29940757 | 0.67 | KDM4E (0.48) | KDM4ECASP1CASP7GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180625-B1 | MODULATING AND NORMALIZING AN IMPAIRED HAEMOSTATIC BALANCE IN A MAMMAL, WHICH METHOD COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF NOVEL BENZOXAZIN DERIVATIVES; ANTICOAGULANTS | NOVO NORDISK A/S (DK) | 2001-01-30 | — | — | US | disclosed |
| WO-1999048878-A1 | HETEROCYCLIC COMPOUNDS REGULATING CLOTTING | NOVO NORDISK A/S (DK) | 1999-09-30 | — | — | WO | disclosed |