Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202564 | 0.91 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL5865480 | 0.91 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL5204210 | 0.89 | PTGS1 (0.53) | PTGS2 | |
| SCHEMBL5201855 | 0.88 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL6169456 | 0.87 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL5204326 | 0.87 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL5205089 | 0.85 | PTGS2 (0.67) | PTGS2 | |
| SCHEMBL5202348 | 0.85 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL5201181 | 0.85 | LMNA (0.47) | PTGS2 | |
| SCHEMBL4674206 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539718-A4 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORP (KR) | 2007-08-01 | — | — | EP | claimed |
| EP-1539718-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ Corporation (KR) | 2005-06-15 | — | — | EP | claimed |
| WO-2004014878-A1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-02-19 | — | — | WO | claimed |