Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 18/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 15/20 | 0.38 |
| ▸ | GABRP | O00591 | 12/20 | 0.38 |
| ▸ | GABRD | O14764 | 12/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.38 |
| ▸ | GABRE | P78334 | 12/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202654 | 0.91 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5206690 | 0.88 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5203133 | 0.85 | GABRB3 (0.35) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5206943 | 0.84 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5204154 | 0.81 | GABRB3 (0.37) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5202633 | 0.81 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8584374 | 0.81 | GABRB3 (0.37) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7028449 | 0.81 | GABRB3 (0.37) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7028447 | 0.80 | GABRB3 (0.36) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL25897 | 0.80 | GABRP (0.51) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948486-B1 | PESTICIDAL 1-ARYLPYRAZOLES | MERIAL LTD (GB) | 2007-11-28 | — | — | EP | claimed |
| EP-0948486-B1 | PESTICIDAL 1-ARYLPYRAZOLES | MERIAL LTD (GB) | 2007-11-28 | — | — | EP | disclosed |
| US-6087387-A | 3-ACETYL-1-PHENYL-PYRAZOLE DERIVATIVES INSECTICIDE USEFUL IN THE CONTROL OF INSECTS, NEMATODES OR HELMINTHS | RHONE-POULENC AGRO (FR) | 2000-07-11 | — | — | US | disclosed |