Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154943 | 1.00 | NPC1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL5202848 | 1.00 | NPC1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL11528034 | 0.98 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL15577072 | 0.98 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL11528037 | 0.98 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL15577073 | 0.98 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL1042803 | 0.95 | — | — | |
| SCHEMBL6902421 | 0.95 | — | — | |
| SCHEMBL9511716 | 0.82 | NPC1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL9511708 | 0.82 | NPC1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103345-A | Method for producing compound comprising isomerization step of alpha, beta-unsaturated ketone | 花王株式会社 | 2024-05-28 | — | — | CN | disclosed |
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | disclosed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | disclosed |
| US-4668827-A | CYCLOHEXANONE, ALIPHATIC ALDEHYDE, OIL IN WATER EMULSIONS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
| US-4395413-A | NICOTINE ANTIALLERGEN, ANESTHETIC, ANALGESIC, HYPOTENSIVE, AND ANTIULCER AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | SORD, PIR, AKR1C4 | NPC1 1460/4885RAB9A 3576/4885MAPT 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.