Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 7/20 | 0.75 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560008 | 0.88 | NR1H2 (0.57) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL822566 | 0.87 | NR1H3 (1.00) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL5202335 | 0.85 | NR1H2 (0.67) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL17336680 | 0.82 | NR1H2 (0.62) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL17279679 | 0.81 | NR1H2 (0.65) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL22307340 | 0.81 | NR1H2 (0.65) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL11555265 | 0.81 | NR1H3 (1.00) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL11590621 | 0.79 | NR1H3 (0.83) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL22307346 | 0.78 | NR1H3 (0.82) | NR1H3NR1H2NPC1RAB9AKDM4C | |
| SCHEMBL17279740 | 0.78 | NR1H3 (0.82) | NR1H3NR1H2NPC1RAB9AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | NR1H3 11/4885NR1H2 10/4885NPC1 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.