Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | GRM6 | O15303 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280475 | 0.97 | GRM4 (0.33) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL27620337 | 0.97 | GRM4 (0.33) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL27601761 | 0.97 | GRM4 (0.33) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL29280477 | 0.97 | GRM4 (0.33) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL6686381 | 0.75 | CYP2C19 (0.35) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL4291628 | 0.73 | SMN1; SMN2 (0.35) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL27788454 | 0.73 | GRM4 (0.35) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL25475447 | 0.73 | — | — | |
| SCHEMBL15876350 | 0.73 | GRM4 (0.33) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 | |
| SCHEMBL6105605 | 0.73 | GRM4 (0.35) | CYP2C19GRM4GRM6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565859-B | Cyclodextrin-bonded object of a kind of chirality platinum-and its preparation method and application | 昆明理工大学 | 2019-09-27 | — | — | CN | claimed |
| CN-103145762-B | Divalence platinum complex containing aryl steric group, preparation method and application thereof | SOUTHEAST UNIVERSITY (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-103224533-B | Alkyl carboxylic acid root containing nitric ether group is anti-tumor platinum (II) title complex of part | SOUTHEAST UNIVERSITY (CN) | 2015-10-07 | — | — | CN | claimed |
| CN-102234295-B | Platinum (II) complex adopting N-alkyl substituted trans 1,2-diaminocyclohexane as ligand and preparation method thereof | UNIV SOUTHEAST | 2014-01-08 | — | — | CN | claimed |
| CN-102260294-B | Binuclear platinum (II) complex or platinum (II) complex and application thereof | UNIV SOUTHEAST | 2013-09-18 | — | — | CN | claimed |
| CN-103224533-A | Antitumor platinum (II) complex by taking alkyl carboxylate radical as ligand | UNIV SOUTHEAST | 2013-07-31 | — | — | CN | claimed |
| CN-103145762-A | Divalent-platinum complex containing sterically-hindered aryl group and preparation method and application thereof | UNIV SOUTHEAST | 2013-06-12 | — | — | CN | claimed |
| CN-102260294-A | Binuclear platinum (II) complex or platinum (II) complex and application thereof | — | 2011-11-30 | — | — | CN | claimed |
| CN-102234295-A | Platinum (II) complex adopting N-alkyl substituted trans 1,2-diaminocyclohexane as ligand and preparation method thereof | UNIV SOUTHEAST | 2011-11-09 | — | — | CN | claimed |
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | claimed |
| CN-106543234-B | Using saturated chain as chiral binuclear platinum complex of bridge and its preparation method and application | 昆明理工大学 | 2019-04-09 | — | — | CN | disclosed |
| CN-104610415-B | Liver target platinum-containing anticancer drug and synthetic method thereof | KUNMING INSTITUTE OF PRECIOUS METALS (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103145762-B | Divalence platinum complex containing aryl steric group, preparation method and application thereof | SOUTHEAST UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103145762-B | Divalence platinum complex containing aryl steric group, preparation method and application thereof | SOUTHEAST UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103764653-B | As compound and the composition of c-Kit kinase inhibitor | IRM LLC (BM) | 2015-12-02 | — | — | CN | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| CN-1821253-A | Novel water soluble Pt (II) anti-cancer ligand and its preparing method | GUIYAN PHARMACEUTICAL CO LTD K (CN) | 2006-08-23 | — | — | CN | disclosed |
| CN-1634946-A | Platinum complex for treating cancer and method for making same | INST OF PRECIOUS METALS KUNMIN (CN) | 2005-07-06 | — | — | CN | disclosed |
| WO-2004099224-A1 | CARBOPLATIN-TYPE PLATINUM (II) COMPLEXES | UNIVERSITÄT REGENSBURG (DE) | 2004-11-18 | — | — | WO | disclosed |