Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203259 | 0.75 | CYP2C19 (0.35) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL11537183 | 0.73 | GRM1 (0.43) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL11820400 | 0.73 | — | — | |
| SCHEMBL1661518 | 0.73 | APLNR (0.36) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL1661517 | 0.73 | GRM4 (0.33) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL15876350 | 0.73 | GRM4 (0.33) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL7140236 | 0.73 | GRM4 (0.56) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL13529287 | 0.73 | GRM4 (0.39) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL6105605 | 0.73 | GRM4 (0.35) | CYP2C19GRM4CYP1A2ALDH1A1TDP1 | |
| SCHEMBL31268151 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099224-A1 | CARBOPLATIN-TYPE PLATINUM (II) COMPLEXES | UNIVERSITÄT REGENSBURG (DE) | 2004-11-18 | — | — | WO | disclosed |